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Family Bank: Cryoviva India

Cryoviva India


Cryoviva Biotech Private Limited was founded in 2006 by RJ Corp. Cryoviva is a healthcare vertical of RJ Corp that is focused on providing high-quality umbilical cord blood stem cell collection, processing and storage. Cryoviva, is India’s foremost premier umbilical cord blood stem cell bank. Cryoviva stands out as the preferred choice for parents deciding to bank their baby’s cord blood stem cells and this has led to more than 3 Lakhs trusted happy families choosing Cryoviva - Bank of Life.

Labs and Locations

129, Pace City -1, Sector-37, Gurugram, Haryana 122001, India

Business Experience

Cryoviva Biotech Private Limited has started Lab Operations in India since 2006 and has a business experience for more than 16 yrs. Cryoviva is a healthcare vertical of RJ Corp. The company RJ Corp is a powerhouse multinational with thriving businesses in beverages, fast-food restaurants, retail, ice-cream, dairy products, healthcare and education. RJ Corp's Varun Beverages Ltd. is one of the largest franchisee of PepsiCo in the world, listed on BSE & NSE in the year 2016. The net worth of Varun Beverages Limited is 41 billion INR. Devyani International Limited is the largest franchisee of Pizza Hut, KFC and Costa Coffee in India, got listed on BSE & NSE in the year 2021. The Devyani International Limited recorded a net worth of 719 million Indian rupees.

Based at Gurugram with networks on PAN India basis. Cryoviva has spread beyond its shores to Thailand, Singapore, Vietnam, UAE, Nepal, Oman, Bahrain, Kenya and East Africa. Cryoviva has their operations in over 15+ countries with laboratories in India, Thailand, Singapore and Vietnam.

Collection Kit

Every Kit Box issued to its clients by Cryoviva is UN3373 certified and contains all the important contents required for collecting the Umbilical Cord Blood, Umbilical Cord Tissue & maternal blood sample. The collection kit contents are:

  • Sterile bag for cord blood collection prefilled with anticoagulant and with a needle protector that helps in preventing accidental pricks.
  • Absorbent pad, alcohol swabs, maternal blood collection vacutainer, povidone iodine prep-pad, sterile plastic cord clamp, parafilm, blood collection needle with luer lock adapter, vacutainer holder and tourniquet, a pair of sterile surgical gloves, gel pack etc.
  • An insulated aluminium foil pouch for the collected cord blood bag which act as shock absorbers as well as long term temperature maintenance thus maintaining the quality of the product. 
  • Two Falcon brand tubes, one for initial decontamination of umbilical cord & the second tube for collection & transportation of umbilical cord tissue to facility.
  • The cord blood, cord tissue & maternal blood sample shall be further put in a secondary leak proof zip lock containers as per the IATA requirement.

Transportation container

The cell quality and viability of the collected cord blood sample is maintained optimally during the transportation with the help of UN3373 certified kit boxes. The kit box is carefully designed to ensure that the optimum temperature as per the regulatory & accreditation requirements is maintained during the transportation of collected samples. The kit box is made up of Thermocol brand fabric with outer hard cardboard & inner Thermocol container (Primary & Secondary container) packing as per the international IATA guidelines. The twin frozen gel packs are used to sandwich the collected cord blood bag, which in turn is packed using a 95 KPA bag, followed by an insulated aluminium foil pouch which act as a shock absorber as well as ensures the optimum temperature. The client receives an acknowledgement email that includes safely processing & storage of their sample in our facility.

Shipping Info

In the event that the cord blood cells are needed for therapy, Cryoviva has procedures to release and ship the sample. Cryoviva requires receipt of written request from the client and also a written requisition from the treating physician. Cryoviva will put in its best efforts to complete the documentation formalities for releasing the product as per the current regulatory norms in co-ordination with the treating physician. Cryoviva shall ship the product/s in an appropriate manner, such as use of controlled monitored cryo-shipper (temperature at or below minus 150°C) throughout the shipment process, in order to provide safe and timely transportation. Cryoviva would offer free shipment worldwide for the product as confirmed during the time of retrieval by the physician.

Processing Method

Purity begins at child birth & so does the preservation of life saving stem cells. It has always been an endeavour of Cryoviva to provide the best technology; hence the first fully automated cord blood processing technology, Sepax was brought to India by Cryoviva in 2009. Cryoviva India follows the “Closed bag” processing protocol under the aseptic environment of laminar flow biological safety cabinets for harvesting cord blood stem cells which greatly reduces the possibility of microbial contamination.

Benefits of Sepax: Safe & highly sterile during processing as completely closed system. Higher stem cells recovery rates of 95 – 99%, with the viability up to 96%. Smooth & precise cell separation as manual intervention is not involved once the sample is loaded. Process every cord blood unit individually in 30-40 minutes, no chance of mix-up of samples thus eliminates any possibility of cross contamination. Used by 70% of the world’s public cord blood banks.

Components Stored

At Cryoviva every cord blood sample is processed as per the best international standards and the following parameters are checked at the time of birth. Details of the test results are provided to each client of Cryoviva in their preservation report.

Maternal Blood Sample: Infectious diseases tests like HIV, Hepatitis B, Hepatitis C, HTLV, CMV, Syphilis, Malaria Infections & NAT (HIV1 RNA, HBV DNA & HCV RNA) are performed at the time of processing and storage. Additional maternal serum & plasma are also preserved for future testing purposes, if any.

Cord Blood Sample: ABO grouping and RH typing, Total Nucleated Cell (TNC) count, Mononuclear Cell (MNC) count, CD34 cell count, cell viability, sterility testing for microbial culture, microbial contamination, Colony Forming Unit (CFU) assay & Hemoglobinopathies.

Cord Tissue: Characterization report (both positive & negative), viability test, sterility, mycoplasma analysis, differentiation potential, endotoxin test, positive surface markers like CD 105, CD73, CD44 & CD90, negative surface markers like CD45, CD34, CD14, CD19 & HLA-DR, characteristics of differentiation into Osteoblasts, Adipocytes & Chondroblasts. All these tests are performed at the time of retrieval upon approval from respective government bodies in India and abroad as per the regulatory protocol of that country.

Additional Testing: HLA typing is performed on the 2nd birth anniversary of the child by Next Generation Sequencing (NGS). If the cord blood unit is retrieved for therapy additional tests are performed at no cost to the client: HLA typing for both donor & recipient by NGS, TNC count, MNC count, sterility test, and viability test.

Storage Method

Cord Blood: The processed Cord Blood is preserved in a FDA-approved multi-compartment cryobag encased between specially designed aluminium cassettes. It is cooled by the standard process of controlled rate freezing and stored in the vapour phase of cryogenic nitrogen until reaching a temperature below -150 degree Centigrade.

Cord Tissue: At Cryoviva, are processed in a WHO-GMP complaint lab using a patented technology of Da Vinci Biosciences, USA. Cryoviva uses explants cell culture method and the cultured MSC will be released as per the current regulatory norms. 

Annual Stability Report: Every year Cryoviva shares an annual stability report to its clients, which shall contain contains statistical details of a donated sample which was stored in the same storage tank of the client. The donated sample is thawed & then tested for sterility, viability, CD34+ count, recovery percentage. Then the report is mapped with the pre-freeze report to check the stability of the specimen. 

Storage Duration: Cryoviva offers clients the option of either a standard storage plan for 21 years or a lifetime plan for 75 years from the birth anniversary of child.

Licensing & Accreditation

Cryoviva is a highly accredited cord blood bank and holds the following accreditations or certifications:

  • Licenced by Drug Controller General of India (DCGI)
  • Accredited by AABB for both Cord Blood and Cord Tissue (Somatic Cells)
  • Accredited by CAP (The College of American Pathologist)
  • Accredited by National Accreditation Board of Testing & Calibration Laboratories (NABL)
  • WHO GMP for Cord Blood and Cord Tissue
  • GLP for Testing of Cellular Therapy products, Cord Blood & Tissue Samples by SGS
  • ISO 9001:2015 certified for Cord Blood and Cord Tissue by ICS

Clinical Experience

Cryoviva medical concierge provides advisory information regarding the usage of stem cells in transplants and may facilitate information on existing transplant programs in India or abroad on client’s request.  Cryoviva has successfully released 33 cryopreserved cord blood units from its Indian facility to treat conditions like Acute Lymphoblastic Leukaemia, Atypical Teratoid Rhabdoid Tumour, Autism Spectrum Disorder, Cerebral Palsy, Meduloblastoma Brain Tumour, and Thalassemia Major. Among the 33 releases, 9 were used for autologous therapy and 24 for allogeneic transplants. Two of the above samples was released to Duke University in USA to participate in the FDA-approved clinical trial for Autism. 


Cryoviva provides clients the options of private or social banking.

  • Financial assistance for cord blood transplant extended to immediate family members up to 20 lakhs until the 21st birth anniversary of the child. (Approved & Clinical Trials)
  • Social banking gives unlimited access to samples without additional cost and protects baby, baby’s biological siblings, biological parents, and biological grandparents (both maternal & paternal).
  • Guaranteed retrieval of cord blood stem cells for immediate family members; in case of HLA mismatch family receives a compensation of 20 lakhs to offset the transplant expense by using other sources of stem cells.
  • High probability of finding a matching cord blood donor in Cryoviva inventory.
  • Disaster relief of INR 20 lakhs for every stem cell transplantation.
  • Quality guarantee of INR 20 lakhs for every stem cell transplantation.
  • Protection against rejection: Continued protection of stem cells for the baby and entire family even if the baby’s cord blood is of low volume / unfit for processing / storage.
  • Free worldwide shipment.
  • Complete accountability of transportation of stem cells across the world from laboratory to the transplant centre.
  • Financial assistance for treatment with Mesenchymal Stromal Cells (MSC) derived from cord tissue is also extended to immediate family members up to 20 lakhs until the 21st birth anniversary of the child (Approved & Clinical Trials)
  • Free MSC expansion up to 1000 million upon approval by respective government bodies in India and abroad.


Private Banking

  • Saver (Cord Blood)- 60,000/- One time, EMI & financing also available till 12 months.
  • Blessings (CB+CT) Sepax -70,000/- One time, EMI & financing also available till 12 months.
  • Supra Superior (CB+CT+50M MSC)- 1,61000/- One time, EMI & financing also available till 12 months
  • Supra Ultimate (CB+CT+500M MSC)- 3,51000/- One time, EMI & financing also available till 12 months

Social Banking

  • Saver (Cord Blood)- 55,000/- One time, EMI & financing also available till 12 months.
  • Blessings (CB+CT) Sepax -75,000/- One time, EMI & financing also available till 12 months.
  • Supra Superior (CB+CT+50M MSC)- 1,61000/- One time, EMI & financing also available till 12 months
  • Supra Ultimate (CB+CT+500M MSC)- 3,51000/- One time, EMI & financing also available till 12 months

Additional Services

Cryoviva offers several additional preventive health care services as:

  • Data Logger Service
  • Newborn Screening- 4 to 104 disorders covered.
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Helpline 24/7: +91 958 228 4444
Toll Free: 1-800-3002-2796
Address: 129 Pace City-1, Sector-37, Gurgaon 122001, Haryana, India