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Odds of use

Legend:

BLUE boxes standard therapies
PINK boxes clinical trials

Odds of a child using its own (autologous)
Cord Blood Stem Cells

Odds Indication
1 in 5,000 in USA Stem Cell Transplant by age 20
#1 cause childhood death in USA:
435,000 per year ages 0-14
Traumatic Brain Injury
1 in 8 (12.5%) kids ages 6-19 in USA Acquired Hearing Loss Prevalence
1 in 68 (1.5%) kids in USA Autism Prevalence
1 in 300 (0.3%) all kids ages 5-10 in USA Cerebral Palsy Prevalence
2 per 1000 (0.2%) babies at full-term birth worldwide Cerebral Palsy Incidence
2.2 per 100 (2.2%) babies at premature birth worldwide Cerebral Palsy Incidence
1 per 3500 births Stroke before or at birth
1.7 per 1000 ages birth-19 Type 1 Diabetes diagnosis rate
0.2 per 1000 at birth Hypoplastic Left Heart Syndrome

Table researched by Frances Verter, PhD ©2014-2016; References Below

Odds of a child using donor (allogeneic, includes siblings) Cord Blood Stem Cells

Odds Indication
1 in 2,500 in USA Stem Cell Transplant by age 20
1 in 2,000 in India Thalassemia births in all of India,
up to 10% of children have Thalassemia in some castes
1 in 4 (25%) premies under 1500gm Premature Lungs (BPD)
1 in 500 worldwide Cerebral Palsy among full term births
(donor stem cell therapy available in S. Korea)
2.5 per 1000 people,
over 80% of them diabetics
Critical Limb Ischemia
1.7 per 1000 ages birth-19 Type 1 Diabetes diagnosis rate
(donor stem cell therapy available in China)
1 in 10 adolescents torn knee cartilage incidence
(stem cell therapy approved in S. Korea, now in USA trials)

Table researched by Frances Verter, PhD ©2014-2016; References Below

References

Lifetime Probability of Stem Cell Transplant in USA

Nietfeld JJ, Pasquini MC, Logan, BR, Verter, F, Horowitz MM 2008; BBMT 14(3)316–322 doi:10.1016/j.bbmt.2007.12.493

Autism

Statistic 1 in 68 children are on the spectrum of autism related disorders is prevalence from CDC.

Cartilage Repair

Statistics on occurance from Louw et al. Brit. J Sports Med 2008;42(1)2-10 doi:10.1136/bjsm.2007.035360

News report on Cartistem approval

Cerebral Palsy

Statistic 2 per 1000 full term births is incidence rate from Centers for Disease Control (CDC)

Statistic 2.2% of premature births from van Haastert IC et al. Pediatrics 2011; 159(1):86-91 doi:10.1016/j.jpeds.2010.12.053

Statistic 1 in 300 children ages 5-10 is prevalence from CDC.

Critical Limb Ischemia

Statistics on occurance from Bitar, FG & Garcia, LA Vascular Disease Management 2010;7:E182-E184

Hearing Loss (cord blood trial is for acquired sensorineural type)

Statistics on 1 per 1000 births with bilateral sensorineural hearing loss of at least 40 dB from

Smith, RJH, Bale Jr, JF, & White, KR. Lancet 2005; 365:879-90 doi:10.1016/S0140-6736(05)71047-3

Statistic: 12.5% of children ages 6-19 (5.2 million) suffer noise-induced hearing loss.

Niskar AS et al. JAMA.1998;279:1071-1075. AAP publications

Animal study: Revoltella RP, et al. Cell Transplant 2008;17(6):665-678 PMID:18819255

Hydrocephalus

Sun JM et al. 2015; Pediatric Research 2015; 78:712–716 doi:10.1038/pr.2015.161

Hypoplastic Left Heart Syndrome

Statistics 0.16-0.36 per 1000 live births from Fyler DC. Pediatrics 1980;65(2Pt2):375-461 (not on-line)

Neonatal Oxygen Deprivation

Statistics Hypoxic Ischemic Encephalopathy (HIE) 2 per 1000 are from Smith, J. etal. BJOG 2000;107(4):461-6 doi: 10.1111/j.1471-0528.2000.tb13262.x

Premature Lungs

Statistics BronchoPulmonary Dysplasia (BPD) 25% babies born wieghing under 1500gm from

Van Marter LJ. Semin Fetal Neonatal Med. 2009;14(6):358-66 doi: 10.1016/j.siny.2009.08.007.

Traumatic Brain Injury

Statistics on occurence from Brain Injury Assoc. of America

Cox Jr., CS et al. Neurosurgery 2011; 68(3):588-600 doi:10.1227/NEU.0b013e318207734c

Type 1 Diabetes

Statistic 1.7 per 1000 ages birth-19 is prevalence from Centers for Disease Control (CDC)

Haller MJ, et al. Diabetes Care 2011;34(12):2567-9. PMCID: PMC3220832

Yong Zhao, et al. BioMed Central Medicine 2012; 10:3 doi:10.1186/1741-7015-10-3

Science Daily Report on diabetes reversal with the "Stem Cell Educator" containing allogeneic cord blood.