CryoCord

CryoCord state-of-the-art laboratory is accredited by Association for the Advancement of Blood and Biotherapies (AABB) and certified to current Good Manufacturing Practice (cGMP) in accordance with (PIC/S) standards set by the NPRA, a division of MOH Malaysia. CryoCord Group holds multiple patents in cell-based technologies and has received several approvals from the MOH for clinical trials involving mesenchymal stem cells (MSCs) and Chimeric Antigen Receptor T-cell (CAR T-cells).

To date, more than 70,000 families have trusted CryoCord to store their valuable stem cells. CryoCord has received numerous accolades, including the Malaysia Stem Cell Banking Company of the Year award by Frost & Sullivan in 2019, and has been voted the Best Stem Cell Bank by Baby Talk Magazine for 14 consecutive years.

Labs and Locations

CryoCord Laboratory
Suite 1-1, 1st Floor, Bio-X Centre,
Persiaran Cyberpoint Selatan, Cyber 8,
63000 Cyberjaya, Selangor,
Malaysia.

Business Experience

STORY

Founded 23 years ago by Professors Dr. Cheong Soon Keng and Dr. Then Kong Yong, CryoCord has grown into a leading and comprehensive medical biotechnology company in the region. Boasting a substantial 65% market share (Frost & Sullivan report), CryoCord’s evolution has expanded from its initial focus on cord blood storage to becoming a fully-fledged cell-based company. Their journey has been marked by consistent growth, including expansion into areas such as mesenchymal stem cells (MSCs), natural killer cells NK cells, Chimeric Antigen Receptor T-cell (CAR T-cells) therapy, and other groundbreaking cell-based research.

In 2006, CryoCord achieved a medical milestone by performing the first successful cord blood transplant in Malaysia using stored sibling’s cord blood for a leukaemia patient at Hospital Kuala Lumpur. In 2009, CryoCord launched a range of mesenchymal stem cell products derived from umbilical cord, bone marrow, fat tissue and tooth pulp — the first of its kind in Southeast Asia. In addition to stem cell banking, CryoCord ventured into immune cell banking services in 2020. This service involves collecting, processing, and cryopreserving immune cells, including NK cells, from one’s blood for potential future use in cell-based therapies.

CryoCord is actively participating in clinical trials to explore innovative therapies for diseases with no satisfactory treatment methods and to address unmet medical needs. Currently, through a subsidiary of the CryoCord group, Plutonet is collaborating with Hospital Canselor Tuanku Muhriz University Kebangsaan Malaysia (UKM) on CAR-T clinical trials for Acute Lymphoblastic Leukemia (ALL) and Non-Hodgkin Lymphoma (NHL) patients. Additionally, CryoCord has obtained approval from the National Pharmaceutical Regulatory Agency (NPRA) under the Ministry of Health (MOH) to conduct a clinical trial with University Malaya (UM) using umbilical cord derived mesenchymal stem cells to treat perianal fistulas in patients with Crohn’s disease.

CryoCord operates from its fully-owned 120,000-square-foot Bio-X Centre, located in the smart city of Cyberjaya, Malaysia. This milestone was achieved without reliance on bank borrowings highlighting the company’s strong financial foundation. The building is supported by a dual-feed power supply from Tenaga Nasional Berhad, ensuring uninterrupted power 24/7, 365 days a year.

TIMELINE

2002
Dr. K.Y. Then and Prof. Emeritus S.K. Cheong envisioned the concept of the establishment of a stem cell cryopreservation bank in Malaysia. CryoCord was created on the talents, skills, experience and vision of a dedicated group of visionary medical and investment professionals.
2003
CryoCord was awarded ISO 14644 Class 5 (Class 100) Cleanroom with HEPA filter, and certified to NASA and US Federal Standard 209E for processing samples.
2004
CryoCord branches in Brunei, Philippines and Thailand are established.
MoU for collaboration on stem cell cryopreservation and research is signed with Intan Medical Centre, Pantai Group of Hospitals and Universiti Sains Malaysia. UKAS and ANAB confer CryoCord ISO 9001:2000 award.
2006
The first successful dual transplant using cord blood stem cells stored by CryoCord and bone marrow stem cells from a sibling is performed at Hospital Kuala Lumpur.
2007
AXP® AutoXpress, the preferred cord blood stem cell processing platform designed and proven to maximize harvest quality, is made available to customers.
A strategic partnership is forged with Cytopeutics, Malaysia’s pioneering stem cell treatment and research group.
2008
CryoCord was awarded umbilical cord blood stem cell banking license, under PHFS Act 1998 by the Ministry of Health, Malaysia.
Sole distributorship of AmnioPlas+ is awarded by USM.
2009
A range of Mesenchymal Stem Cell (MSCs) storage services is launched.
CryoCord was also awarded ISO 15189 certification by Laboratory Accreditation Scheme of Malaysia (SAMM).
2011
CryoCord Jakarta office established in Mega Kuningan, Indonesia.
2012
Acquisition of a BioNexus company, StemTech International Sdn Bhd, which was once a subsidiary of the Bursa listed TMC group.
Baby Talk Magazine awarded CryoCord its Inaugural Best Stem Cell Bank, among all the stem cell banking companies in Malaysia.
2013
CryoCord takes pride of place in its new Group Corporate Headquarters at Bio-X Centre, Cyberjaya. This architecturally stunning and purpose designed building is the new integrated seat of group management, administration, and laboratories.
For the second year running CryoCord garners Baby Talk Magazine’s Best Stem Cell Bank Award.
State of the art laboratory certified to cGMP (PIC/S) requisites was awarded by NPCB (BPFK), a division of the Ministry of Health, Malaysia.
2014
For the third year in a row CryoCord is awarded Best Stem Cell Bank award by BabyTalk Magazine.
CryoCord has extended its serviced by offering Contract GMP-Manufacturing and Research.
Collaboration with UKM Ophthalmology Medical Centre (PPUKM) advances stem cells research in retina regeneration.
2015
CryoCord is awarded Best Stem Cell Bank for four consecutive years.
2016
CryoCord has been awarded Best Stem Cell Bank award by BabyTalk Magazine for the fifth time.
CryoCord has garnered The BrandLaurete’s Best Brands in Sciences – Stem Cell Laboratory.
2017
CryoCord awarded as the Best Stem Cell Bank for the sixth consecutive time.
CryoCord has been awarded Sin Chew Business Excellence Award by Sin Chew Daily.
CryoCord received the prestigious Sun Yat-Sen Enterprise Award from Kwong Wah Yit Poh Press Bhd.
2018
For the 7th time, CryoCord bagged the Best Stem Cell Bank Award by Baby Talk Magazine.
CryoCord has been awarded Best Stem Cell Bank by Parenthood Magazine.
International Natal Care Awards 2018 awarded CryoCord the Most Trusted Stem Cell Bank – Favourite Natal Care Service.
2019
CryoCord retains Best Stem Cell Bank Award by Baby Talk Magazine, for the 8th consecutive year.
CryoCord honoured with the 2019 Malaysia Stem Cell Banking Company of the Year award by Frost & Sullivan at the Asia-Pacific Best Practices Awards.
CryoCord has been Best Stem Cell Bank for the 2nd consecutive year by Parenthood Magazine.
Motherhood Choice 2019 Stem Cell Bank Award was awarded to CryoCord.
CryoCord bagged Pa&Ma 2019 Preferred Stem Cell Bank Award
2020
CryoCord achieved accreditation by AABB (Association for the Advancement of Blood and Biotherapies).
CryoCord built the First Biosafety Level 2 (BSL-2) GMP facility in Malaysia.
First CAR-T clinical trial approved in Malaysia, a collaboration between Plutonet (a member of the CryoCord Group) and Hospital Canselor Tuanku Muhriz (HCTM) UKM, for Acute Lymphoblastic Leukemia (ALL) and Non-Hodgkin Lymphoma (NHL).
2021
Collaboration with University Malaya with approval from NPRA on the use of MSC to treat perianal fistula in patients with Crohn’s disease.
2022
Induced pluripotent stem cells (iPSCs) storage services made available in CryoCord.
2023
For the 12th consecutive year, CryoCord has received the Best Stem Cell Bank Award from Baby Talk Magazine.
Parenthood Magazine has recognised CryoCord as the Best Stem Cell Bank for the 6th consecutive year.
2024
For the 13th consecutive year, CryoCord has received the Best Stem Cell Bank Award from Baby Talk Magazine.
Parenthood Magazine has recognised CryoCord as the Best Stem Cell Bank for the 7th consecutive year.

Collection Kit

CryoCord’s CordBlood and CordMSCs collection kits are specially designed to comply with AABB and IATA standards. The collection kits have successfully passed temperature stability and drop tests. CryoCord uses specially designed sterile cord blood collection bag (FDA approved) to maximise the volume of the cord blood upon collection and a specially designed container for CordMSCs. It has a custom designed foam for enhanced temperature control during transportation and has a tamper-evident sticker to improve security after collection.

Transportation container

CryoCord’s collection kits include a temperature logger to consistently monitor sample temperature throughout the logistic process adhering to National Standards for Cord Blood Banking and Transplantation Malaysia.

Processing Method

Fully automated system: AXP® II AutoXpress Platform, which is US FDA approved.

Components Stored

The components consisting of Total Nucleated Cells (TNC) including the Hematopoietic Stem Cells (HSC) are provided with a report describing test results as below:
1. Cord blood volume (TNC count)
2. Cell count
3. Stem cell viability
4. Sterility

Storage Method

CryoCord offers two types of storage method for cord blood stem cells:

Single-use Cryobag.
Multi-compartment storage for multiple usage.

Licensing & Accreditation

Fully licensed by Ministry of Health Malaysia (MOH) under PHFS Act 1998.
cGMP according to PIC/S standards by National Pharmaceutical Regulatory Agency (NPRA), a division of the Ministry of Health Malaysia
Accredited by AABB (Association for the Advancement of Blood and Biotherapies).
Certified to ISO 15189 by SAMM (Laboratory Accreditation Scheme of Malaysia)
First Biosafety Level (BSL-2) GMP facility audited by Biosafety Board Malaysia.

Insurance

Great Eastern General Insurance (Malaysia), a member of the OCBC group, offers an insurance plan that covers the cost of cord blood stem cell transplantation (inclusive of Celebral Palsy) exclusively for CryoCord clients.
They also offer comprehensive value added programs for their clients.

CryoCare Enhanced: Guarantees coverage for cord blood stem cells transplantation cost.*

CryoMatch: Covers the cost of one-time acquisition of viably matching stem cells unit.*

CryoMove: Guarantees against the loss or non-viability of stem cells during transportation to and from storage facility.*

CryoSure: Guarantees money-back payment in the event your child’s stem cells are not viable when there is a need to use for treatment.*

CryoFree: Guarantees waiver of annual storage fees until the child reaches 21 years old in the event of either parents' demise.*

3G: Covers 3 generations.*

Community Service

CryoCord Community Transplantation Program offers enrollment for cord blood stem cells storage at no cost to expecting mothers whose immediate family members are suffering from blood disorders such as leukaemia, thalassemia or any other disease that can be treated using cord blood stem cells. It is one of the many ways we keep in touch with the things that make our community a caring one. Eligible applicants will be given a free collection, processing and storage for the first year.

Prices

The enrolment fee ranges from RM3,500 to RM13,300 depending on the type of services. The annual storage fee for CordBlood and CordMSCs is RM350 and RM430 respectively. This fee will be reduced if you choose to pay years in advance. 0% easy payment plans are available.

Additional Services

Perinatal Cells

CordCELLS – Isolation, and storage of mesenchymal stem cells (MSC) derived from the umbilical cord Wharton’s Jelly.
CordMSCs – Isolation, expansion and storage of mesenchymal stem cells (MSC) harvested from the umbilical cord Wharton’s Jelly.
CordPSCs-i- Reprogramming cord blood stem cells into induced pluripotent stem cells (iPSCs).
EP- Freeze-dried extracellular particles derived from umbilical cord mesenchymal stem cells

Adult MSCs

ToothMSCs- Isolation, expansion and storage of mesenchymal stem cells harvested from the tooth pulp.
MarrowMSCs – Isolation, expansion and storage of mesenchymal stem cells harvested from the bone marrow.
AdiMSCs - Isolation, expansion and storage of mesenchymal stem cells harvested from the fat tissue.

Adult Stem Cells

AdultPBSCs - – Isolation and storage of hematopoietic stem cells harvested from the peripheral blood.
Imunecel- Processing and storage of immune cells, such as natural killer (NK) cells, from peripheral blood.
CAR-T- Genetic modification of T-cell to express specific chimeric antigen receptors (CARs) that target cancer cells.

Phone:

Free 24 Hours: 1-800-88-3300
Office: +603 8689 8888

Address: Suite 1-1, Bio-X Centre, Persiaran Cyberpoint Selatan, Cyber 8, 63000 Cyberjaya, Selangor, Malaysia

URL

https://cryocord.com.my/