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Family Bank: Cryoviva

Cryoviva Thailand


Cryoviva (Thailand) Ltd., a family stem cell bank, has been operating since 2007, has AABB accreditation since 2010, and has expanded their service to store cord tissue, amnion/placental membrane, adipose tissue and to culture Mesenchymal Stem Cells (MSC) from these sources. The company has experience in shipping the stored cord blood/cord stem cells for transplantation. The company has expanded their service to cover 22 countries with processing done at their labs in Thailand, Singapore, and India.

Labs and Locations

Bangkok Office: 75/66,67 Ocean Tower 2, 41st Floor, Soi Sukhumvit 19, Bangkok, 10110 Thailand

Laboratory Location (45 minutes from central Bangkok): 35/8 Moo 4, Tambol Khunkaew, Amphur Nakornchaisri, Nakon Pathom 73120 Thailand

Business Experience

Cryoviva (Thailand) Ltd., was established in 2007.  The company has provided the service of cord blood collection and storage for clients since 2008.  In 2010, services were expanded to cover the collection of cord tissue, and presently mesenchymal stem cells from the Wharton jelly, amnion/placental membrane and adipose tissue are also collected, expanded and stored.

 Cryoviva is embarking on expansion into a number of services which will provide a benchmark for the stem cell industry in Thailand. These include:

  • Insurance program for treatments,
  • QA/QC testing laboratory for cellular and gene therapy products (including MSC-ID, a unique method to test ownership of cells which have been expanded),
  • International education program in stem cells for both general consumers and healthcare professionals, aimed to increase general awareness and disease specific knowledge related to stem cells.

Currently, there are almost 15,000 cord blood units and more than 1.5 trillion mesenchymal stem cells expanded and stored.  In addition, units have also been transported and used successfully in transplants and treatments.

Collection Kit

Collection kits are prepared separately for cord blood, umbilical cord/amnion tissue, and adipose cells.  The materials required for collection are contained within a disposable strong cardboard box with which has the company’s information printed on it, along with important warnings such as "Do Not Pass Through X-Ray Device", "Keep at Room Temperature", "To Avoid Cord Blood Unit Rejection, Volume is Important in Each Collection".

The standard cord blood collection bag is specifically manufactured for cord blood collection consisting of needle guard to cover the sharp end of a needle.  The bag is packed in a sterile plastic bag. The collection kit also contains a 95 kPa biohazard bag to ensure safe transportation and a gel pack to help maintain proper temperature conditions. Other items included are blood sample tubes, labels, alcohol and povidone-iodine pads as well as "cord blood delivery information form" and instruction for cord blood collection. Cord/placenta/fat collection kit also have their unique designed kit for proper collection to ensure quality collection compliance to the standard as the same.

Transportation container

A gel pack has been provided in the collection kit which will be help to maintain the temperature of the the cord blood unit at a temperature between 15-25 degrees C for about 4 hrs. If the travel time will take more than 4 hrs, the collection box will be packed in a standard transportation box with appropriate amount of ice-packs. The temperature during transportation will be recorded by a temperature data logger.

Shipping Info

Shipping of units are arranged through company-owned transportation, contracted air cargo, or internationally accepted courier companies.  Transportation of the units from the hospital to the facility is free of cost within Thailand and at actual cost from overseas.

Processing Method

The cord blood sample will be processed by either one of these methods as appropriate: Manual cell separation by sedimentation by adding HES and spin, or Automated cell separation using Sepax equipment from Biosafe.  For tissue banking, the cord/placenta/adipose tissue will be manually processed  according to international accepted and published protocol, in compliance with ISCT (International Society of Cell & Gene Therapy) guidelines.

Components Stored

For cord blood units, parents are provided with a certificate and lab test results of cord blood stem cells and maternal blood.  The cord blood unit and stem cells will be tested for the volume of cord blood collected, ABO and Rh typing, Total Nucleated Cells (TNC) count, viability (%), Hb electrophoresis.  The maternal sample will be tested for ABO and Rh typing, Infectious Disease Markers such as Syphilis, HBV, HCV, HIV, CMV, and NAT for HBV, HCV, and HIV.

The buffy coat holding white cells and stem cells plus 3 segments attached to the units are stored as well as an aliquot sample of maternal serum and cord blood. The red blood cells and plasma components of the unit will be kept at 4 degrees C for at least a month for additional testing if required before being discarded. 

For cord/amnion/placental tissue, there are two options for the parents: One is to immediately cryopreserve the tissue after collection, the second is  to grow Mesenchymal Stem Cells from cultures of the tissue and then store the cells.  The latter is more desirable due to the much higher number of  stem cells derived from the family’s limited valuable source and is also better in terms of economic production scale.

Storage Method

For cord blood, the final product is filled into two compartments of a freezing bag, encased in an overwrap bag and metallic cassette. For  other tissue sources, the final product is stored in cryovials. In either case, the  unit's temperature is then slowly decreased with the use of a controlled rate freezer and then finally stored in the vapor phase of a liquid nitrogen tank.

Licensing & Accreditation

Cryoviva (Thailand) is accredited by the international stnadards AABB and ISO 9001. Cryoviva (Thailand) was awarded with Frost & Sullivan’s Stem Cell Company of the Year Award in Thailand 2015, 2016 and 2017.  For 2018, the  Stem Cell Company Growth Excellence Leadership award was received.

Clinical Experience

Cryoviva (Thailand) has released client cord blood units for transplantation of siblings suffering from Thalassemia and also several MSC units for regenerative disease therapies, rejuvenation and aesthetic treatments.


Financial compensation and expenses relating to searching and obtaining a replacement unit and transplant financial assistance are also provided to clients.  Cryoviva is in the process of developing financial compensation options to cover all family members for treatments using stem cells.

Community Service

Free banking is provided to qualified families where the baby’s sibling has a diagnosis for which transplantation is determined as the option for treatment.  In addition, Cryoviva has also set up a fund to assist those in need of a stem cell transplant.


Prices range from US$3,000 to US$10,000 depending on the package and storage services chosen by the client.  Additional packages for cell culture are available and quotations will be provided on request.

Additional Services

The company offers additional services for the expansion and banking of cells from Wharton's Jelly/amnion/placental membrane/adipose tissue.  In addition, predictive testing, QA/QC testing for cellular and gene products are available.

Prices with Additional Services

Prices for other services combined with cord blood storage range up to US$ 120,000.

Free Call Center: +66 (1) 800-545-555
Office: +66 02 661 6661
Address: 75/66,67 Ocean Tower 2, 41st Floor, Soi Sukhumvit 19, 10110 Bangkok, Thailand