Newsletter - November 2015


Cord Blood Industry Report

Frances Verter, PhD & Pedro Silva Couto, MSc

Parent's Guide to Cord Foundation has issued the world's first Cord Blood Industry Report that is based on direct interviews of family cord blood banks around the world. All participating companies were promised confidentiality, hence their proprietary data is only presented in aggregates. The landing page of the report displays an Abstract of the contents, and the Access page explains the subscription procedure. In this article we present a preview of some interesting results.

One of the biggest inaccuracies that plagued previous reports about the cord blood industry was confusion over what constitutes a cord blood bank. We define a family cord blood "Bank" (with a capital B) as an entity that owns and operates a laboratory. It is common for a single Bank to market its services through multiple "Affiliates" in multiple countries. Collectively, there are at least 434 "Providers" (both Banks and Affiliates) of family cord blood banking worldwide, but only 214 of them are Banks.

The distinction between Banks and Affiliates matters, depending on what parameter of cord blood banking is being examined. For example, prices are set at the Provider level, whereas accreditations can only belong to the laboratory of a Bank. In our report we sometimes found differences between the average prices of Banks versus Affiliates for certain services.

Our Foundation has been publishing cord blood industry reports for over a decade, but this is the first year that we are issuing the report on a secure website through a shopping cart. Back in 2003, the Parent's Guide to Cord Blood found that, within the US, the inventory in family banks was 3.0 times larger than the inventory in public banks. A decade later in 2013, our worldwide survey of family banks counted an inventory at least 3.4 times higher than the public inventory reported by WMDA for the same time stamp. This shows that claims of wild growth in the family banking sector are a bit misleading. While family banks are active on a much larger scale than public banks, the inventory disparity between family and public banks today is similar to the disparity that existed a decade ago.

Under the current clinical operations of family cord blood banks, in which cord blood units are primarily released for sibling transplants or for autologous-use clinical trials, the world's largest family banks have achieved release rates between 10 and 100 per 100,000 inventory. We have previously published an excerpt of our report that calls out the rapid growth of sibling transplants for thalassemia in Asia, a situation where family cord blood banks are filling a public health need that is not adequately met by public banks. Our report also reviews the use of autologous cord blood therapy for pediatric brain injuries.

The biggest unique feature of our 2015 report is that we have compiled all the available prices for both cord blood banking and cord tissue banking, converted them to the same currency (USD), and performed numerous statistical studies to see how price is related to other banking parameters. Below is an excerpt of 20-year prices (processing & 20 years of storage) for selected countries that have 5 or more providers of family cord blood banking; the error bars are standard deviations.

Prices Cord Blood & Cord Tissue

This graph previews one of our conclusions: In European countries the price of cord tissue banking is usually half the price of cord blood banking, whereas in Asia & Oceania the prices of these two services are comparable.

We have developed a new metric called the Parent's Guide Price IndexTM (PGPITM) that adjusts the price of family stem cell storage for the economy of the country where the provider does business. The PGPITM is defined as the ratio of the 20-year price for storing perinatal stem cells, divided by the annual income of households in the top 10% of the nation's GDP. The top 10% income in the denominator is intended to represent those households that are most likely to purchase family cord blood banking. Below we display the PGPITM of cord blood and cord tissue storage for the same set of selected countries, when possible.

PGPI<sup>TM</sup> Cord Blood & Cord Tissue

While the absolute prices of cord blood storage are highest in North America and Western Europe, the PGPITM metric shows that in these countries cord blood and cord tissue storage are actually the most affordable, because 20 years of cord blood storage only costs 2% of the annual household income for families in the top 10%. The PGPITM of cord blood and cord tissue storage is about 8% in Latin America and close to 20% in some Asian countries. The underlying trend is that PGPITM is high in countries that have large income disparities.

One of the biggest revelations in our report is that highly accredited family cord blood Banks do not cost consumers any more than Banks with no accreditation. The most common accreditation category for family cord blood Banks around the world is None, holding 36% of Banks. The other two large accreditation categories are ISO alone (holding any ISO accreditations) at 30%, and AABB and/or FACT (with or without ISO) at 28%. A 6% fraction of cord blood banks are accredited by National Authorities who require facility inspections. AABB and FACT are the only voluntary accreditations that are specifically designed for cord blood laboratories, thus we consider them to be the gold standards. Below are the average prices and standard deviations of these categories.

Price versus Accreditation (Banks, Worldwide)

It turns out that there is no statistically significant difference between the average price of family cord blood Banks with None accreditation versus the AABB and/or FACT group. Cord blood laboratories that have attained the highest quality compliance are not passing their cost of accreditation on to consumers. Parents should be encouraged to select family banking providers that use laboratories with AABB and/or FACT accreditation, because there is usually no extra cost to choosing the highest quality.

We surveyed family Bank laboratories about their cord blood processing and found that many continue to use the traditional manual methods, and in some countries those methods are dominant. We surveyed the Providers to find out which blood bags they are using for cord blood collections, and identified over 21 brands of bags. The type of bag most commonly named by Providers is "proprietary" bags, in which a cord blood company has taken a vendor's bag and customized it.

Cord Blood Processing by Geographic Region

Regardless of whether or not Mesenchymal Stromal Cells (MSC) are "Ready for Prime Time", family storage of umbilical cord tissue has become a norm in this industry. Half of all family cord blood Banks now offer this service. The figure below shows that the availability of cord tissue storage varies geographically. At present 13% of those Banks offering cord tissue storage offer it as stand-alone service.

We found that offering cord tissue storage enables Banks to be more competitive: Those cord blood Banks that offer multiple stem cell storage services have significantly lower prices for cord blood storage alone. We also found that Banks who offer cord tissue storage tend to be more highly accredited for their cord blood storage; their most common cord blood accreditations are AABB and/or FACT at 40%, ISO alone at 28%, and None at 25%.

Cord Blood & Cord Tissue Storage by Geographic Region

One chapter of our report is devoted to a survey of the cord tissue processing methods that are currently in use among family cord blood Banks, and a review of the literature supporting the various processing options. There is great deal of variation in the laboratory procedures and prices being offered for cord tissue storage. Roughly half of the Banks that process cord tissue are storing a tissue product (either whole or minced umbilical cord), and only a third of them are definitely storing isolated cells.

Managers of cord blood Banks who only operate in one region of the world may feel it is not a priority for them to be aware of all the international trends in our report. However, any Bank manager who is currently offering or plans to offer cord tissue storage would benefit from our survey of how other cord blood Banks are managing this emerging service and how their choices impact their ability to set prices.

We anticipate that the year ahead will bring significant changes to the landscape of cord tissue storage. We expect that more Banks will adopt tools from Miltenyi or AuxoCell that semi-automate cord tissue processing and produce more standardized products. AABB offers a somatic cell accreditation which can be used to accredit isolation of MSC from cord tissue. Those Banks that have this AABB accreditation can point to it as a discriminator, which will create market pressure for other Banks that store cord tissue to obtain accreditation for cell isolation activities and/or demonstrate that they have validated their protocols.

Parent\'s Guide to Cord Blood Foundation logo Whatever the future brings to the industry of perinatal stem cell storage, Parent's Guide to Cord Blood Foundation will endeavor to help consumers make educated choices for their families.


CBR & NAHN Partner to Heighten Awareness of Cord Blood Options

partnership NAHN & CBR

In July 2015, Cord Blood Registry® (CBR®) and the National Association of Hispanic Nurses® (NAHN®) announced that the two organizations have entered into a collaboration focused on educating health care providers and the public about the importance of preserving cord blood stem cells. Through active counseling to promote informed decision making by Latina expectant mothers, CBR and NAHN will strive to reach an increasing number of Hispanic families that may benefit from the storage or donation of cord blood stem cells. The partnership will offer cord blood stem cell education and outreach to Hispanic nurses in the form of continuing medical education, materials support, and online resources for those healthcare professionals working with Latino expectant parents.

To help Hispanic families make an informed decision, it is critical that healthcare providers be able to counsel and offer bilingual educational materials. The inclusion of diversity is central to CBR's health education initiatives. Please click here to access CBR's Spanish-language patient education resource.


Planting Seeds One Community at a Time

Alana Cueto, MSN, RN, CNL, Founding President, National Association of Hispanic Nurses - Garden State Chapter

Garden State NAHN Board of Directors (& Dr. Verter)

Left to Right: Claudia Pagani, MSN, RN-BC, NAHN President-Elect; Frances Verter, PhD, Parent's Guide to Cord Blood; Alana Cueto, MSN, RN, CNL, NAHN Founding President; Diana Torres, BSN, RN, NAHN Advocacy Chair; Viviana Lozano, BSN, RN, NAHN Marketing Chair; Carmen Torres, PhD (s), MSN, MHS, RN, NAHN Treasurer

Hispanics in the State of New Jersey now comprise the largest minority, making up nearly 18% of the State's population or roughly 1.5 million residents (US Census Bureau, 2010). Despite the nursing profession numbering 3 million registered nurses in the United States, only 3.6% of these are Hispanic, or of Latino origin (AACN Diversity in Nursing, 2015). At the local and state level the National Association of Hispanic Nurses (NAHN) Garden State Chapter was formed to help bridge the equity and health disparities that exist within Hispanic communities in New Jersey (NJ).

"Planting Seeds One Community at a Time" is the motto of Garden State NAHN. The chapter's focus is primarily on education, advocacy, and collaboration. Garden State NAHN achieves its motto by forging relationships with community partners, schools of nursing, and local hospitals. Garden State NAHN believes that by aligning its resources with community partners it can eliminate redundancies, and promote communication and team building that serves to enhance optimal care for the most susceptible populations. Nurses understand that we do not work in silos! This mindset is carried into our partnerships so we can collaborate and pool resources to better serve our local Hispanic communities.

Since the chapter's inaugural launch in January 2015, Garden State NAHN has been pro-active in alternating its monthly chapter meetings between a hospital and a school of nursing. We cover both the Northern and Southern regions of the state to include those counties that comprise the largest number of Hispanic residents.

Garden State NAHN also stays true to its motto by contributing to each town or city that hosts its monthly chapter meeting. Community service is at the essence of caring for our most vulnerable populations. We do this on an on-going basis through various community events such as Food Drives - helping to restock the shelves at a local food pantry, serving hot meals at local soup kitchens, and collection of granola bars and juice packs to donate to a local after-school program.

Frances Verter, PhD & Alana Cueto, MSN, RN, CNL

Frances Verter of Parent's Guide to Cord Blood Foundation with Alana Cueto, MSN, RN, CNL, Founding President of Garden State Chapter of National Association of Hispanic Nurses

Garden State NAHN and its individual members have partnered with the media and with community programs in numerous joint efforts that provide bilingual health education directly to Hispanic communities and/or have provided us a forum to promote nursing as a profession for our Hispanic youth, thus helping to increase diversity in nursing as well as promoting a culture of health for all Hispanics. These are just a few examples of activities completed to date by the Garden State NAHN team members.

In May, Garden State NAHN hosted its first continuing education session leading to one professional contact hour titled, Impact of Sexual Assault and Domestic Violence on Women's Health. At this session, all attendees were asked to donate baby items that were delivered to a local woman's prenatal clinic. Additionally, Garden State NAHN held its First Annual Education Symposium & Scholarship Awards Lunch on October 17th. This event was built around empowering nursing students through networking and providing continuing education for registered professional nurses. This event had three educational tracks: student, leadership, and clinical track, leading to six (6) contact hours.

In November, Garden State NAHN will be hosting an educational session for its members about cord blood collection and storage. The session will review its history, current science, and future value. This session will serve to educate the nurse members and student members so they in turn can better educate and advocate for the communities they serve.

Garden State NAHN is committed to being inclusive and it welcomes all nurses, healthcare providers and affiliate stakeholders to join its chapter. We recognize that nurses and health care providers from diverse backgrounds care for Hispanic patients - and their families - and we invite them to share their insight by joining us! To learn more, visit us on-line at or follow us via LinkedIn, Twitter (@gardenstateNAHN) or Facebook.

Garden State NAHN LOGO Alana Cueto, MSN, RN, CNL, is 2015 Nurse Fellow of the New York Academy of Medicine and Founding President, National Association of Hispanic Nurses Garden State Chapter. Alana has a Bachelor of Science in Healthcare Management from New York University and a Master of Science in Nursing, with a concentration in Clinical Nurse Leadership, from Seton Hall University. Alana has over two decades of experience in the healthcare delivery system. That time has been divided between hospital administration, dental and medical consulting, nursing and higher education. She has held many leadership roles in both private and public health, and in the for- and not-for profit health sectors.


  1. American Association of Colleges of Nursing | Diversity in Nursing. (2015, March 16). Retrieved from
  2. New Jersey QuickFacts from the US Census Bureau. (2010). Retrieved from