Registration Of All Clinical Trials Mandated

The International Committee of Medical Journal Editors (ICMJE) has mandated registration of all clinical trials, and Pharmaceutical Research and Manufacturers of America (PhRMA), are requiring that both negative and positive results from pharmaceutical trials be reported in detail and made publicly available. "We know that some clinical trials, especially those with results unfavorable to drug companies, are never published," said Gregory D. Curfman, MD, executive editor of the New England Journal of Medicine (NEJM). Although the ICMJE does not recommend one particular registry, they suggest that only www.clinicaltrials.gov, sponsored by the U.S. National Library of Medicine (NLM), currently meets all of the recommended criteria.