Cryoviva

About

Cryoviva (Thailand) Ltd. is the only AABB accredited family cord blood bank in Thailand. The company has been operating since 2007 and has expanded their service to store cord tissue and to culture Mesenchymal Stem Cells from the Wharton’s Jelly part of the cord tissue. The company has experience in shipping the stored cord blood stem cells for transplantation. The company has expanded their service to cover 22 countries including Myanmar, Cambodia, Vietnam, Laos, and others. 

Labs and Locations

Bangkok Office:
75/66,67 Ocean Tower 2, 41st Floor, Soi Sukhumvit 19, Bangkok, 10110
Thailand

Laboratory Location (45 minutes from central Bangkok):
35/8 Moo 4, Tambol Khunkaew, Amphur Nakornchaisri, Nakon Pathom 73120
Thailand

Business Experience

Cryoviva (Thailand) Ltd. was launched with technology licensed from Lifeforce Cryobanks (previously known as Cryobanks Intnl.). The company has set up and marketed cord blood banking since 2007.  The company has provided the service of cord blood collection and storage for clients since 2008.  From 2010, we have expanded our services to collect cord tissue as well as cord blood.  We have stored approximately 5,000 cord blood stem cell units and almost 1,000 cord tissue units in our facility.  We have our own cell culture lab within our group of companies and have coordinated and transported stem cell units for transplant successfully.

Collection Kit

We have prepared separate cord blood and cord tissue collection kits.  The materials required for collection are contained within a disposable strong cardboard box with printed name-logo of the company as well as important information such as "Do Not Pass Through X-Ray Device", "Keep at Room Temperature", "To Avoid Cord Blood Unit Rejection, Volume is Important in Each Collection".

The cord blood collection bag is specifically manufactured for cord blood collection.  Each bag has two needles with different lengths of tubing lines, each customized for use for normal vaginal delivery or C-section.  Both lines consist of needle guard to cover the sharp end of each needle.  The bag is packed in a sterile plastic bag which is then placed in aluminum foil, which, with proper handling, will ensure the bag remains sterile both inside and outside. 

The collection kit also contains a 95 kPa biohazard bag to ensure safe transportation and a gel pack to help maintain proper temperature conditions. Other items included are blood sample tubes, labels, alcohol and povidone-iodine pads as well as "cord blood delivery information form" and instruction for cord blood collection.

Transportation Container

A gel pack has been provided in the collection kit which will be help to maintain the temperature of the the cord blood unit at a temperature between 15-25 degrees C for about 4 hrs.  If the travel time will take more than 4 hrs, the collection box will be packed in a standard blood bank transportation box with appropriate amount of ice-packs.  The temperature during transportation will be recorded by temperature data logger.

Shipping Info:

Shipping of cord blood units are arranged by our company through our van, contracted air cargo in Thailand or an authorized courier (World Courier) for overseas shipping.  Transportation of the cord blood unit from the hospital to our facility is free of cost for within Thailand and at actual cost from overseas.

Processing Method

The sample will be processed by either one of these methods as appropriate: Manual cell separation by sedimentation by adding HES and spin, or Automated cell separation using Sepax equipment from Biosafe.

Components Stored

Parents are provided with a certificate and lab test results of cord blood stem cells and maternal blood.  The cord blood unit and stem cells will be tested for the volume of cord blood collected, ABO and Rh typing, Total Nucleated Cells (TNC) count, viability (%), Hb electrophoresis.  The maternal sample will be tested for ABO and Rh typing, Infectious Disease Markers such as Syphilis, HBV, HCV, HIV, CMV, and NAT for HBV, HCV, and HIV.

The buffy coat holding white cells and stem cells plus 3 segments attached to the units are stored as well as an aliquot sample of maternal serum and cord blood. The red blood cells and plasma components of the unit will be kept at 4 degrees C for at least a month for additional testing if required before being discarded.

Storage Method

The final product is filled into two compartments of a freezing bag, encased in an overwrap bag and metallic cassette.  The unit's temperature is then slowly decreased with the use of a controlled rate freezer and then finally stored in the vapor phase of a liquid nitrogen tank.

Licensing & Accreditation

Cryoviva (Thailand) is accredited by AABB and IS9001.

Clinical Experience

Cryoviva (Thailand) has released client cord blood units for transplantation of siblings suffering from Thalassemia.

Insurance

Financial compensation and expenses relating to searching and obtaining a replacement unit and transplant financial assistance are provided at different amounts depending upon the Cryoviva package chosen by the client.

Community Service

Cryoviva (Thailand) will give discounts to medical doctors, nurses and staff of the company.  We have also provided free banking to families where the baby’s sibling has a diagnosis for which transplantation is indicated.  The company has also set up a fund to assist those in need of a stem cell transplant.

Prices

Prices range from US$3,000 to US$10,000 depending on the package and storage services chosen by the client.  Additional packages for cell culture are available and quotations will be provided on request.

Additional Services

The company offers additional service for Wharton's Jelly banking and Mesenchymal Stem Cell culturing from cord tissue.

Prices with Additional Services

Prices for other services combined with cord blood storage range up to US$ 20,000.